DNA is a large molecule that stands for deoxyribonucleic acid, while RNA is a large molecule that stands for ribonucleic acid. DNA is made of two intertwining strands of deoxyribonucleotides, while RNA is made up of a single strand of ribonucleotides. The 5-carbon sugar in DNA is deoxyribose, and the 5-carbon sugar in RNA is ribose. In RNA, the base uracil (U) replaces the base thymine (T) that is found in DNA. Because of this, the DNA alphabet is A-T-C-G, while the RNA alphabet is A-U-C-G. One main role of RNA is to transfer the genetic code needed for the creation of proteins at the ribosome. Other types of RNA assist protein synthesis at the ribosome by providing the synthesis site and by supplying the necessary amino acids (note: function of RNA is dependent on the RNA type). The main role of DNA is to store and transmit genetic information (DiscoveryEducation).